معلومات عن المنتج
|المواد الفعاله بالتفصيل||لا|
|دواعي الإستعمال||Antodine® Injection is indicated in some hospitalized patients with pathological hypersecretory conditions or intractable ulcers, or as an alternative to the oral dosage forms for short term use in patients who are unable to take oral medication for the following conditions: Short term treatment of active duodenal ulcer. Most adult patients heal within 4 weeks; there is rarely reason to use Antodine® at full dosage for longer than 6 to 8 weeks. Studies have not assessed the safety of Antodine® in uncomplicated active duodenal ulcer for periods of more than eight weeks. Maintenance therapy for duodenal ulcer patients at reduced dosage after healing of an active ulcer. Short term treatment of active benign gastric ulcer. Most adult patients heal within 6 weeks. Short term treatment of gastroesophageal reflux disease (GERD). Antodine® is indicated for short term treatment of patients with symptoms of GERD. Antodine® is also indicated for the short term treatment of esophagitis due to GERD including erosive or ulcerative disease diagnosed by endoscopy. Treatment of pathological hypersecretory conditions (e.g., Zollinger-Ellison Syndrome, multiple endocrine adenomas)|
|طريقة الاستعمال و الجرعه||In some hospitalized patients with pathological hypersecretory conditions or intractable ulcers, or in patients who are unable to take oral medication, Antodine® (Famotidine) injection may be administered until oral therapy can be instituted. The recommended dosage for Antodine® (Famotidine) injection in adult patients is 20 mg intravenously every 12 h.|
|موانع الاستعمال||Hypersensitivity to any component of these products. Famotidine should not be administered to patients with a history of hypersensitivity to other H2-receptor antagonists.|
|الاعراض الجانبيه||The following adverse reactions have been reported to occur in patients on therapy with famotidine: headache, dizziness, constipation and diarrhea. The following other adverse reactions have been reported infrequently in clinical trials or since the drug was marketed. The relationship to therapy with famotidine has been unclear in many cases. Within each category the adverse reactions are listed in order of decreasing severity: Body as a Whole: fever, asthenia, fatigue Cardiovascular: arrhythmia, AV block, palpitation Gastrointestinal: cholestatic jaundice, hepatitis , liver enzyme abnormalities, vomiting, nausea, abdominal discomfort, anorexia, dry mouth. Hypersensitivity: anaphylaxis, angioedema, orbital or facial edema, urticaria, rash, conjunctival injection. Musculoskeletal: musculoskeletal pain including muscle cramps, arthralgia. Nervous System/Psychiatric: grand mal seizure; psychic disturbances, which were reversible in cases for which followup was obtained, including hallucinations, confusion, agitation, depression, anxiety, decreased libido; paresthesia; insomnia; somnolence. Respiratory: bronchospasm. Special Senses: tinnitus, taste disorder.|
No drug interactions have been identified with Antodine® (Famotidine) as it does not interfere with the disposition of compounds metabolized by the hepatic microsomal enzymes, e.g., cytochrome P450 system. e.g. warfarin, theophylline, phenytoin, diazepam, aminopyrine and antipyrine.
Pregnancy: Pregnancy Category B This drug should be used during pregnancy only if clearly needed.
eneral Symptomatic response to therapy with Antodine® (Famotidine) does not preclude the presence of gastric malignancy. Patients with Moderate or Severe Renal Insufficiency Since CNS adverse effects have been reported in patients with moderate and severe renal insufficiency, longer intervals between doses or lower doses may need to be used in patients with moderate (creatinine clearance
Nursing Mothers: Famotidine is detectable in human milk. Because of the potential for serious adverse reactions in nursing infants from Famotidine , a decision should be made whether to discontinue nursing or discontinue the drug, taking into account the importance of the drug to the mother.
|طريقة التخزين||Store Antodine® (Famotidine) injection at 2° to 8°C (36° to 46°F). If solution freezes, bring to room temperature; allow sufficient time to solubilize all the components. Diluted solutions of Antodine® (Famotidine) injection should be refrigerated and use|
|الجرعه||حقنة مرة واحدة يوميا|